Guanggancao Ding is derived from the plant Guangguo licorice. Belonging to the licorice flavonoid family. In the experiment, it was found that it has superior performance in anti-inflammatory, anti-tumor, anti-aging, and whitening aspects. Guanggancao Ding mainly inhibits tyrosinase activity through competitive inhibition, removing a portion of tyrosinase from the catalytic ring of melanin synthesis, preventing substrate binding with tyrosinase, thereby inhibiting melanin synthesis. At the same time, Guanggancao Ding itself has excellent antioxidant properties.
1: Low solubility and poor water dispersibility
2: Poor stability, unstable light and heat, and prone to discoloration
3: Poor transdermal absorption and low bioavailability
1. High stability: effectively improves the light/heat stability of glycyrrhizin
2. High compatibility: Good water dispersibility, easy to mix with various substrates, especially suitable for transparent systems
3. High bioavailability: Active ingredients with different whitening mechanisms synergistically enhance efficacy, promote transdermal absorption of active ingredients into the whitening target site, and effectively improve bioavailability
Invention patent: A high skin retention light glycyrrhizin nanocomposite and its preparation method and use
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