1、 Introduction to raw materials
Coenzyme Q10, also known as ubiquinone 10, is a lipid soluble quinone with a structure similar to vitamin K. It is named after the polymerization degree of the side chain at the sixth position of its parent nucleus, polyisoprene, which is 10. It is a quinone ring compound that can promote skin metabolism, inhibit skin lipid peroxidation, and has a more significant nourishing and activating effect on the skin than vitamin E and vitamin B.
2、 Application pain points
1: Coenzyme Q10 is extremely unstable to light and heat, easily degraded, and prone to deactivation
2: Coenzyme Q10 is insoluble in water and has poor compatibility with the matrix
3: Coenzyme Q10 is difficult to penetrate through the skin and enter the anti-aging target areas such as the dermis layer and target cells such as skin fibroblasts
3： Product advantages
1. High stability: effectively improves the photo/thermal stability of coenzyme Q10
2. High compatibility: easy to mix various matrices such as cream/essence/lotion/water agent/facial mask, suitable for transparent system
3. High bioavailability: The transdermal carrier promotes the transdermal absorption of coenzyme Q10, entering the skincare target area and target cells, effectively acting on cell mitochondria, and improving the bioavailability of coenzyme Q10
4、 Patents and Papers
Invention Patent: Coenzyme Q10 Nanolipid Composition and Its Preparation Method and Application (Patent No.: ZL201010557948.9)
Published papers: Siyuan Chen, Wei Liu, Jiang Wan, et al. Preparation of Coenzyme Q10 Nanostructured Lipid Carriers for Epidermal Targeting with High Pressure Microfluidics Technique [J] Drug Development and Industrial Pharmacy, 2012 : 1–9
