1、 Introduction to raw materials
Salicylic acid has multiple functions and can solve various problems that cause acne, so a large number of acne products on the market contain salicylic acid to some extent. The bactericidal effect of salicylic acid is also an important reason for its use in removing acne. For decades, dermatologists have been using salicylic acid to exfoliate and remove accumulated acne and dirt from pores, effectively fighting acne, including improving whiteheads and blackheads, while also exerting some anti-inflammatory effects. Studies have also found that it can increase skin thickness, enhance skin barrier function, and promote collagen synthesis. Salicylic acid with a concentration of 0.5% -2% has milder properties, similar to fruit acid, and can exert exfoliating effects on the skin surface.
2、 Application pain points
1: Low solubility and poor water dispersibility
2: Poor stability, prone to discoloration
3: Reduce matrix viscosity
4: Difficult to apply to transparent formulas
5: Strong skin irritation
3: Product advantages
1. Low irritation: Carrier technology can slow down the release of salicylic acid and reduce irritation
2. High compatibility: easy to mix with various substrates and can be applied to transparent systems.
3. High bioavailability: Carrier technology can promote rapid penetration of salicylic acid into the stratum corneum of the skin, penetrate deep into the cyst site, and effectively improve bioavailability
4、 Patents and Papers
Invention patent: A salicylic acid nanocomposite and its preparation method and application (patent number: 202111266430.4)
Published article: Preparation, in vitro release behavior, and antibacterial activity of salicylic acid nanoemulsion