1、 Introduction to raw materials
Retinol is a natural vitamin A, and its derivatives are called retinoids. The retinoid family includes retinol, retinoic acid (RA), retinyl esters, beta carotene, etc. Many classic brands and products use retinoids as the first choice for antioxidant, anti-aging, and acne treatment. Due to the instability of retinol, most commercially available products are retinol derivatives. Retinol palmitate is one of the retinol derivatives, with a molecular formula of C36H60O2. It is an ester that combines retinol with palmitic acid, resulting in less irritation and relatively warmer efficacy. However, retinol palmitate has a larger molecular weight and slower permeability.
2、 Application pain points
1: Poor stability, sensitive to air, heat, light, and temperature, and susceptible to losing physiological effects when exposed to ultraviolet radiation
2: Difficult to be absorbed through the skin, VA targets the dermis layer and needs to be absorbed through the skin to exert its effects.
3： Product advantages
1. High stability: effectively improves the photo/thermal stability of VA palmitate
2. Small particle size: The particle size is small and finely uniform, with excellent stability
3. High compatibility: easy to mix various matrices such as cream/essence/lotion/water agent/facial mask, suitable for transparent system
4. High bioavailability: slow-release and controlled release, increasing the retention of VA palmitate in the skin and improving bioavailability
