1、 Mechanism of action
Androgenic alopecia is the most common type of hair loss, also known as seborrheic alopecia, accounting for 90% of all hair loss. This product is designed to target androgenic alopecia and contains active ingredients targeting different targets. It stimulates the proliferation of hair follicles and papilla cells, dilates blood vessels, strengthens and solidifies hair, optimizes hair cycle, and accelerates new hair growth from the perspectives of inhibiting the level of II-5 α reductase in hair follicles, promoting the expression of messenger ribonucleic acid (m-RNA), inhibiting lysine hydroxylase, and opening potassium channels.
2、 Application pain points
1. Limited effectiveness in preventing hair loss: Anti hair loss products generally have unclear mechanisms, single targets, and overuse of conceptual ingredients, resulting in limited effectiveness in preventing hair loss.
2. The product has significant side effects: some students may experience relapse after discontinuing the medication, which can lead to side effects such as obesity, emotional depression, and decreased physical strength.
3. Low utilization rate of active ingredients: The anti hair loss active ingredients are difficult to penetrate into hair follicles and cannot directly act on the target area, greatly reducing the anti hair loss effect.
4. Poor product experience: Most commercially available products are tinctures containing ethanol and penetration enhancers, which can cause dry scalp, dandruff, itching, and damage to the skin.
3: Product advantages
1. High stability: By utilizing the protective effect of the carrier, the anti hair loss active ingredients remain stable under various conditions.
2. Synergistic effect enhancement: Reasonably mix the anti hair loss ingredients of different targets to achieve the strongest anti hair loss effect.
3. High bioavailability: With the excellent transdermal performance of the carrier, it can quickly penetrate into the hair follicle target site and enter the anti hair loss target cells, significantly improving the high bioavailability.
4. High drug loading: increases the content of active ingredients in anti stripping products.
5. Easy to apply: can be directly compounded with hair growth water and other products.
4、 Patents and Papers
Invention patent: A nanocomposite containing diaminopyrimidine oxide and pyrrolidine diaminopyrimidine oxide, its preparation method and application (patent number: ZL 2019 1 0036145. X)
Published papers:
Preparation and efficacy evaluation of anti hair loss active substance co delivery nanoliposomes [J] Daily Chemical Industry, 2020, 50 (6): 6
Preparation and anti hair loss efficacy of diaminopyrimidine oxide/matrine/oleanolic acid composite nanoliposomes [J] Fine and Specialty Chemicals, 2021
In vitro anti hair loss study of pyrrolidine diaminopyrimidine oxide/adenosine/active peptide composite nanoliposomes [J] Daily Chemical Science, 2021
Study on the efficacy of dipropylene glycol/squalane/trimethylolpropane trioctylate caproate composite nano nipple skin care and hair repair, spice essence cosmetics, 2021