In recent years, the efficacy cosmetics market in China has been growing rapidly. With the promulgation and implementation of the national "Regulations on the Supervision and Administration of Cosmetics" and a series of implementation rules, the Chinese cosmetics market will face the strictest regulatory supervision in the world. At present, more and more consumers are beginning to realize the importance of cosmetic efficacy, and the rise of the "ingredient party" has also made many skincare brands pay more attention to the addition of functional ingredients, hoping to obtain high-performance exclusive functional ingredients. The starting point of the "ingredient party" is functional ingredients, but high concentration does not equal high efficacy. Long term use of high concentration and high dose functional ingredients can cause irreversible damage to the skin's microecology. The correct way to apply cosmetic ingredients is to achieve high efficacy with minimal dosage, low sensitivity, and high efficiency. The R&D team of Wuhan Baisi Kairui Biotechnology Co., Ltd. has been deeply involved in the field of nano carrier transdermal absorption for more than 20 years. By using co delivery nanocarrier technology to promote transdermal absorption of cosmetic functional ingredients with different mechanisms of action, the functional ingredients are stored in the skincare target area and enter the target cells, achieving sustained release, controlled release, and long-lasting effects, effectively improving the bioavailability of cosmetic functional ingredients, and achieving low sensitivity and high efficiency.
Since the beginning of this year, the development of new functional ingredients in cosmetics has entered the fast lane. According to the announcement of the National Medical Products Administration, the NMN cosmetic raw material filing submitted by three companies has been approved. NMN, also known as β - nicotinamide mononucleotide, is a precursor to NAD+(coenzyme I), which is closely related to energy metabolism, glycolysis, DNA replication, and other activities in the human body. Therefore, NMN, which can increase NAD+levels in the human body, is considered a promising anti-aging cosmetic ingredient with broad application prospects. Wuhan Baisi Kairui Company has seized the trend of cosmetic efficacy raw material development, laid out in advance, and developed NMN transdermal co delivery nanocarrier products with NMN as the core efficacy ingredient. The Chinese invention patent "A Targeted Mitochondrial Skin Anti Aging Nanocomposition and Its Preparation Method and Application (Patent No. 202110165249.8)" applied for has recently been authorized. This patented technology constructs a transdermal co delivery nanocarrier by targeting mitochondrial anti-aging active substance NMN with protein synthesis promoters, anti-aging agents, etc. It applies dual targeting technology to promote the penetration of functional ingredients through the skin barrier into deep skin tissues, increasing the entry of functional ingredients into anti-aging target cells and cell mitochondria, thereby significantly improving the bioavailability of functional ingredients such as NMN and enhancing their anti-aging effects.
Wuhan Baisi Kairui Company has recently obtained authorization for Chinese invention patents, including: a multi effect hydroxyquinone retinate nanocomposite and its preparation method and application (patent number: CN202110175444.9); A composite of multiple hyaluronic acid nanoparticles and its preparation method and application (patent number: CN202110175456.1). The former uses transdermal co delivery nanocarrier technology to scientifically combine quadruple vitamins A/B/C/E, synergistically increasing efficiency. The currently available product name is Transnova^TMHPR CT. The latter scientifically combines multiple hyaluronic acids and uses transdermal co delivery nanocarrier technology to significantly improve the skin penetration and retention of hyaluronic acid, with sustained and long-lasting release. The currently available product name is Best Carrier^®Five fold HA.